Anti-Inflammatory Effects of Jojoba

A recent study has revealed that Jojoba has anti-inflammatory properties. Inflammation of the scalp, specifically around the follicles, has been linked to alopecia. If the follicles remain healthy they can recycle continuously throught a persons life, meaning hair for life. However inflammation can permenantly destroy stem cells which are key to the continual regeneration of all self renewing tissues including the hair follicle. Inflammation can also cause hairs to shed at a faster rate. Jojoba is already recognised as one way of keeping scalp sebum levels healthy, so it’s total effect may be two fold in the prevention of hair loss.

Anti-inflammatory effects of jojoba liquid wax in experimental models.

Pharmacol Res. 2005 Feb;51(2):95-105.

Habashy RR, Abdel-Naim AB, Khalifa AE, Al-Azizi MM.

Department of Pharmacology and Toxicology, Ain Shams University, Cairo, Egypt.

Jojoba [Simmondsia chinensis (Link 1822) Schneider 1907] is an arid perennial shrub grown in several American and African countries. Jojoba seeds, which are rich in liquid wax, were used in folk medicine for diverse ailments. In the current study, the potential anti-inflammatory activity of jojoba liquid wax (JLW) was evaluated in a number of experimental models. Results showed that JLW caused reduction of carrageenin-induced rat paw oedema in addition to diminishing prostaglandin E2 (PGE2) level in the inflammatory exudates. In a test for anti-inflammatory potential utilizing the chick’s embryo chroioallantoic membrane (CAM), JLW also caused significant lowering of granulation tissue formation. Topical application of JLW reduced ear oedema induced by croton oil in rats. In the same animal model, JLW also reduced neutrophil infiltration, as indicated by decreased myeloperoxidase (MPO) activity. In addition, JLW ameliorated histopathological changes affected by croton oil application. In the lipopolysaccharide (LPS)-induced inflammation in air pouch in rats, JLW reduced nitric oxide (NO) level and tumor necrosis factor-alpha (TNF-alpha) release. In conclusion, this study demonstrates the effectiveness of JLW in combating inflammation in several experimental models. Further investigations are needed to identify the active constituents responsible for the anti-inflammatory property of JLW.

PMID: 15629254 [PubMed - indexed for MEDLINE]

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve…

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This article was written on October 17, 2005 was posted in these categories Studies & News .